Honokiol is a potent scavenger of superoxide and peroxyl radicals
نویسندگان
چکیده
منابع مشابه
Plasma marker of tissue oxidative damage and edaravone as a scavenger drug against peroxyl radicals and peroxynitrite
The percentage of the plasma oxidized form of coenzyme Q10 in the total amount of coenzyme Q10 (%CoQ10) is a useful marker of oxidative stress in the circulation. Plasma free fatty acids and their composition can be used as markers of tissue oxidative damage, as demonstrated in patients suffering from a wide variety of diseases and in humans and rats under oxidative stress. Edaravone was approv...
متن کاملCalixtyrosol: a Novel Calixarene Based Potent Radical Scavenger
The oxidative stress causes many diseases in human, therefore antioxidants have a specialposition in the medicinal chemistry. Tyrosol is an important antioxidant with a plenty ofbiological properties. There are many strategies such as clustering single drug units in orderto develop new drugs. The cluster effect can increase drug effects relative to single drug unit.Calixtyrosol is the novel clu...
متن کاملCalixtyrosol: a Novel Calixarene Based Potent Radical Scavenger
The oxidative stress causes many diseases in human, therefore antioxidants have a specialposition in the medicinal chemistry. Tyrosol is an important antioxidant with a plenty ofbiological properties. There are many strategies such as clustering single drug units in orderto develop new drugs. The cluster effect can increase drug effects relative to single drug unit.Calixtyrosol is the novel clu...
متن کاملPeroxyl free radicals: potential mediators of tumor initiation and promotion.
In recent years, there has been an explosion of interest in the involvement of free radicals in carcinogenesis (1 -4) . This seems a natural outgrowth of the long overdue realization that free radicals are formed in biological systems and that they contribute significantly to physiological and pathological processes. Much of the emphasis of research linking free radicals and cancer has focused ...
متن کاملPeroxyl radicals are potential agents of lignin biodegradation.
Past work has shown that the extracellular manganese-dependent peroxidases (MnPs) of ligninolytic fungi degrade the principal non-phenolic structures of lignin when they peroxidize unsaturated fatty acids. This reaction is likely to be relevant to ligninolysis in sound wood, where enzymes cannot penetrate, only if it employs a small, diffusible lipid radical as the proximal oxidant of lignin. H...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biochemical Pharmacology
سال: 2008
ISSN: 0006-2952
DOI: 10.1016/j.bcp.2008.06.012